Their conclusion sums it up quite nicely: …Garcinia extractsHCA can cause short-term weight loss. The magnitude of the effect is small, and the clinical relevance is uncertain. I agree. It may cause a mild effect in some people, but overall the effects are small and unlikely to make a major difference Bottom Line: There have been many studies conducted on Garcinia Cambogia in overweight individuals. Some of them show a small amount of weight loss, while other studies show no effect.